Thesis, internship, and post-doc opportunities
[Thèse]
Study of chemically functionnalized Si nano-devices applied to biological detection in liquid environment
Offer N°: 2569
The detection and quantification of chemical species and biological markers (DNA, antibodies, cancer markers) are crucial in the fields of health and life science for applications such as medical diagnosis or the identification of molecules to develop medicine. Novel detection methods based on electronic devices are highly promising compared to traditional techniques (e.g. fluorescence, mass detection, pH...) in terms of resolution and potential for integration in complex systems.
The detection and quantification of chemical species and biological markers (DNA, antibodies, cancer markers) are crucial in the fields of health and life science for applications such as medical diagnosis or the identification of molecules to develop medicine. Novel detection methods based on electronic devices are highly promising compared to traditional techniques (e.g. fluorescence, mass detection, pH...) in terms of resolution and potential for integration in complex systems. This PhD is part of an ongoing project at LETI whose goal is to evaluate electrical biological detection based on a CMOS technology in real biological conditions. The long-term application that is aimed is the development of a portable/point of care miniaturized system. The work will be conducted in collaboration with the CLSE laboratory (Swiss up chair in engineering) at EPFL, specialized in the design and characterization of electrical integrated sensors, sensitive to biological molecular species.