MINA-NEWS
Proteomic analysis: a high-performance lab-on-chip
Labs-on-chip are not only smaller and cheaper than conventional testing instruments, but they can also perform better. This is true for Léti’s most recent prototypes containing a nanochromatographic column with micropillars made on the MEMS200 platform using a deep etching process and an electrospray ionization (ESI) source that can interface directly with a mass spectrometer. The pillars’ submicron size gives the system excellent separation power, and the fact that the source and column are located on the same component prevents the risk of degradation during sample transportation.
Tests will be conducted on a brain and lung cancer marker at concentrations of around 50 ng/mL to assess the system’s performance.
Contact: pierre.grangeat@cea.fr ; nicolas.sarrut@cea.fr
